An AGM-114 Hellfire is an air-to-ground missile (as is indicated by the "AGM" abbreviation) used by AH-64 Apache gunships and can be deployed by high-altitude Predator drones. It is a weapon and scorechain in Medal of Honor (2010).
Hellfire missiles are only usable at certain points, when Gunfighter 11 marks a target for Gunfighter 06. they are capable of destroying any target, and are very precise, although they are slow moving.
In multiplayer, the AGM-114 Hellfire is the Coalition weapon for the missile strike Support Action, usable after gaining 175pts in any life. It can be manually guided and is capable of killing large groups of OpFor players easily due to the large explosion.