The 116th Infantry Regiment is the name of the regiment that attacks a section of Omaha Beach in Medal of Honor: Frontline. Lt.Jimmy Patterson is attached to it during the first two missions of the game. The 116th Infantry Regiment formed as a part of the Virginia Militia in 1741. During World War 2 the 116th was attached to the 29th Infantry Division. In 1975 the 116th Infantry Division became part of 116th Infantry Brigade. The 116th currently deployed in the Middle-East.
The 116th appears in Frontline's first two levels as part of the 29th Infantry Division. Despite the heavy losses the 116th managed to capture Omaha Beach with the help of OSS Agent James Patterson.